Apixaban concentration variability and relation to clinical outcomes in real-life patients with atrial fibrillation

A Mavri, N Vene, M Božič-Mijovski, M Miklič… - Scientific Reports, 2021 - nature.com
… over time and the association of trough and peak apixaban … of anticoagulant treatment for
each patient with atrial fibrillation. The … partial thromboplastin time (APTT) (Pathromtin SL) and …

Clot time ratio (CTR) and treatment outcomes in Apixaban-treated atrial fibrillation patients

L Onelöv, M Božič-Mijovski, A Mavri - Scientific Reports, 2024 - nature.com
Apixaban at trough and peak, and to evaluate association between PT DOAC expressed in
Clot Time Ratio CTR and clinical outcomes in patients with atrial … run prothrombin time assays…

Apixaban enhances endogenous fibrinolysis in patients with atrial fibrillation

N Spinthakis, Y Gue, M Farag, M Srinivasan… - EP …, 2019 - academic.oup.com
… effect of apixaban on endogenous fibrinolysis in patients with non-valvular atrial fibrillation
(NVAF). … to maximal thrombus growth and coagulation, 17 prolonged clotting time and time to …

Direct oral anticoagulants plasma levels in patients with atrial fibrillation at the time of bleeding: a pilot prospective study

I Škorňová, M Samoš, T Bolek… - Journal of …, 2021 - journals.lww.com
… observations) favor an association between high rivaroxaban … will be needed for a final
confirmation of this association. … K Antagonist Treatment) trial enrolling apixaban-treated patients

Effect of apixaban compared with warfarin on coagulation markers in atrial fibrillation

C Christersson, L Wallentin, U Andersson… - Heart, 2019 - heart.bmj.com
… without substantial association with lower risk of stroke/SE.18 Elevated F1+2 levels have
been described in stroke patients with AF, and as F1+2 levels reflect thrombin generation they …

Evaluation of Apixaban safety and effectiveness in morbidly obese patients with atrial fibrillation: a retrospective cohort study

K Al Sulaiman, HA Badreldin, GB Korayem… - Thrombosis …, 2022 - Springer
… with nonvalvular atrial fibrillation (AF) is still undetermined. The International Society of
Thrombosis and Hemostasis recommends avoiding the use of direct … Partial thromboplastin time

Clinical implications of assessment of apixaban levels in elderly atrial fibrillation patients: J-ELD AF registry sub-cohort analysis

S Suzuki, T Yamashita, M Akao, K Okumura… - European Journal of …, 2020 - Springer
Association between the blood apixaban concentration estimated by anti-Xa assay and
prothrombin time with four different reagents. The scatter plot is displayed separately by standard …

Effectiveness and safety of apixaban compared with rivaroxaban for patients with atrial fibrillation in routine practice: a cohort study

M Fralick, M Colacci, S Schneeweiss… - Annals of internal …, 2020 - acpjournals.org
prothrombin time (a measure associated with anticoagulant activity) and higher trough
prothrombin time with apixabanSociety guidelines for the management of atrial fibrillation. Can J …

Evaluation of newly‐developed modified diluted prothrombin time reagent in non‐valvular atrial fibrillation patients with direct oral anticoagulants: A comparative study …

O Kumano, S Suzuki, M Yamazaki, Y An… - International Journal …, 2023 - Wiley Online Library
… PT reagents even in the presence of on-therapy concentrations of apixaban. Therefore, PT
has not been … or assessing the intensity of anticoagulation at on-therapy doses for apixaban. …

The correlations between anti-factor Xa activity values and PT/APTT at peak and trough times in patients with venous thromboembolism using high dose of apixaban

R Ono, K Fukushima, T Yamazaki… - European Heart …, 2020 - academic.oup.com
… Although patients taking direct oral anticoagulants do not require routine coagulation …
markers such as prothrombin time (PT) and activated partial thromboplastin time (APTT) at peak …